Without proper treatment, half of the 370,000 children newly infected with HIV last year will die before they reach their second birthday. But very few medicines are designed and adapted specifically for children, and are affordable and practical to use in the places where they live. The Drugs for Neglected Diseases initiative (DNDi) recently announced a new project to help develop appropriate HIV drugs for children.
For centuries, the drug quinine has been used to treat malaria, a disease that kills close to one million people a year. But now, there’s a new drug - called artesunate - that is more effective, and far simpler and safer to administer than quinine. The WHO has just revised its guidelines calling for artesunate as the treatment of choice for children with severe malaria. Now the international community needs to get behind it.
XDR-TB stands for extensive drug resistant tuberculosis. Drugs for TB have not been improved in four decades; they cause terrible side effects and require the patient to take numerous pills every day for between six months and three years. While one in five patients under treatment for moderately resistant strains of the disease do not survive, patients with extensively resistant cases, if they can get treatment at all, usually must rely on less effective and more toxic medicines, with lower success rates. For these reasons and others, Xoliswa Armans is a remarkable patient.
We take you to northern Nigeria, where MSF is providing surgery to repair fistulas – life-altering internal injuries that can happen to women who endure prolonged, complicated labor. In Burkina Faso, malnutrition is at its annual peak and MSF is responding.We’ll hear from an MSF doctor who was there at the same time last year. You'll also hear emergency updates from MSF projects around the world.