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Medical Research

Medical data and research from Doctors Without Borders/Médecins Sans Frontières (MSF) field operations are regularly published in the peer-reviewed literature.

Below is a selection of recently published MSF medical research articles. For copies or to search all MSF research publications, please visit the MSF Field Research website, or contact Dr. Patricia Kahn, Medical Editor, patricia.kahn[at]newyork.msf.org.

MSF research articles on Sleeping Sickness

May 26, 2011

Challenges of controlling sleeping sickness in areas of violent conflict: experience in the Democratic Republic of Congo

Jacqueline Tong, Olaf Valverde, Claude Mahoudeau, Oliver Yun, Francois Chappuis
Confl Health 2011;5:7
Conflict and Health

Democratic Republic of the Congo, Sleeping Sickness

February 1, 2010

Human African trypanosomiasis in areas without surveillance [letter]

François Chappuis, Maria Angeles Lima, Laurence Flevaud, Koert Ritmeijer
Emerg Infect Dis 2010;16(2):354-6.
Emerging Infectious Diseases

Central African Republic, Democratic Republic of the Congo, Sleeping Sickness

June 24, 2009

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: A multicentre, randomised, phase III, non-inferiority trial

Gerardo Priotto, Serena Kasparian, Wilfried Mutombo, Daniel Ngouama, Sara Ghorashian, Ute Arnold, Salah Ghabri, Elisabeth Baudin, Vincent Buard, Serge Kazadi-Kyanza, Médard Ilunga, Willy Mutangala, Gabriele Pohlig, Caecilia Schmid, Unni Karunakara, Els Torreele, Victor Kande
Lancet 2009;374:56-64

Congo, Democratic Republic of the Congo, Neglected Diseases, Sleeping Sickness

October 22, 2008

Effectiveness of melarsoprol and eflornithine as first-line regimens for gambiense sleeping sickness in nine Médecins Sans Frontières programmes

Manica Balasegaram, Heather Young, François Chappuis, Gerardo Priotto, Marie-Eve Raguenaud, Francesco Checchi
Transactions of the Royal Society of Tropical Medicine and Hygiene 2009;103:280-290. (doi: 10.1016/j.trstmh.2008.09.005)

Neglected Diseases, Sleeping Sickness

March 5, 2008

Safety and effectiveness of first line eflornithine for Trypanosoma brucei gambiense sleeping sickness in Sudan: Cohort study

Gerardo Priotto, Loretxu Pinoges, Isaac Badi Fursa, Barbara Burke, Nathalie Nicolay, Guillaume Grillet, Cathy Hewison, Manica Balasegaram
BMJ 2008;336:705-708. (doi: 10.1136/bmj.39485.592674.BE)

Neglected Diseases, Sleeping Sickness, Sudan

February 8, 2008

Estimates of the duration of the early and late stage of gambiense sleeping sickness

Francesco Checchi, Joao A.N. Filipe, Daniel T. Haydon, Daniel Chandramohan, Francois Chappuis
BMC Infectious Diseases 2008;8:16. (doi: 10.1186/1471-2334-8-16)

Neglected Diseases, Sleeping Sickness, Sudan, Uganda

February 1, 2008

Eflornithine is a cost-effective alternative to melarsoprol for the treatment of second-stage human West African trypanosomiasis in Caxito, Angola

J Robays, ME Raguenaud, T Josenando, M Boelaert
Tropical Medicine & International Health 2008;13:265-271. (doi: 10.1111/j.1365-3156.2007.01999.x)

Angola, Neglected Diseases, Sleeping Sickness

November 7, 2007

Nifurtimox plus eflornithine for late-stage sleeping sickness in Uganda: A case series

Francesco Checchi, Patrice Piola, Harriet Ayikoru, Florence Thomas, Dominique Legros, Gerardo Priotto
PLoS Neglected Tropical Diseases 2007;1:e64. (doi: 10.1371/journal.pntd.0000064)

Neglected Diseases, Sleeping Sickness, Uganda

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