August 2012, in the village of Karangasso, district of Koutiala, Mali. For the first time, MSF is rolling out a large-scale in-situ strategy for the preventive treatment of malaria, called seasonal malaria chemoprevention (SMC), in a pilot projects in Mali. Antimalarial treatments have been administered to some 165,000 children aged between 3 months and 5 years old. The initial results are highly encouraging, with a 65% drop in the number of malaria cases. Furthermore, the number of malaria-associated hospitalisations plummeted from 228 to 70 per week.