Stephane did his first humanitarian mission in Sierra Leone in 1996 as a logistician with Action Contre La Faim (ACF). After four additional field missions in Africa as logistician and then head of mission, he joined the ACF Parisian Headquarters in 2000 as the chief of operational logistics and then becoming the Desk for Asia Programs.

In 2003, Stephane joined MSF as a head of mission in Sierra Leone and then Colombia. In 2006, he coordinated the advocacy Campaign against malnutrition of MSF with OCP and the Access Campaign, working in MSF's Paris headquarters. Stephane then worked in Dakar for OCBA from 2013 to 2016, setting up a new regional support unit for MSF programs in West Africa. Since November 2, 2016, he has been the Cell Manager of the New York Desk.