HIV/AIDS treatment and management are essential components of many MSF programs worldwide. Currently MSF provides antiretroviral therapy (ART) for over 140,000 patients in 27 countries, with about 10,000 of those patients being children. In conjunction with this year’s International AIDS Conference in Mexico City, this document presents MSF’s current “state of play” in providing quality care to people living with HIV/AIDS (PLWHA) in resource-limited settings.